Datasets:

vector-institute
/

open-pmc-18m

json dict	__key__ stringlengths 8 8	__url__ stringclasses 100 values
{ "caption": "C66 and SP600125 attenuate LPS-induced inflammatory cell infiltration. Before LPS administration, mice were given by gavage once a day for 7 consecutive days of C66 (5 and 10 mg/kg) and SP600125 (10 mg/kg). After 6 hrs of LPS challenge, we euthanized mice and then took out lung tissue and BALF. (A) Tota...	00000000	hf://datasets/vector-institute/open-pmc-18m@0d97c202058f2ac1b33438ec35e4b37b31ad3a41/data-000000.tar
{ "caption": "C66 and SP600125 attenuate LPS-induced inflammatory cell infiltration. Before LPS administration, mice were given by gavage once a day for 7 consecutive days of C66 (5 and 10 mg/kg) and SP600125 (10 mg/kg). After 6 hrs of LPS challenge, we euthanized mice and then took out lung tissue and BALF. (A) Tota...	00000001	hf://datasets/vector-institute/open-pmc-18m@0d97c202058f2ac1b33438ec35e4b37b31ad3a41/data-000000.tar
{ "caption": "C66 and SP600125 attenuate LPS-induced inflammatory cell infiltration. Before LPS administration, mice were given by gavage once a day for 7 consecutive days of C66 (5 and 10 mg/kg) and SP600125 (10 mg/kg). After 6 hrs of LPS challenge, we euthanized mice and then took out lung tissue and BALF. (A) Tota...	00000002	hf://datasets/vector-institute/open-pmc-18m@0d97c202058f2ac1b33438ec35e4b37b31ad3a41/data-000000.tar
{ "caption": "C66 and SP600125 attenuate LPS-induced inflammatory cell infiltration. Before LPS administration, mice were given by gavage once a day for 7 consecutive days of C66 (5 and 10 mg/kg) and SP600125 (10 mg/kg). After 6 hrs of LPS challenge, we euthanized mice and then took out lung tissue and BALF. (A) Tota...	00000003	hf://datasets/vector-institute/open-pmc-18m@0d97c202058f2ac1b33438ec35e4b37b31ad3a41/data-000000.tar
{ "caption": "Characteristics of the CASF/Ad complex. (A) Scanning electron microscopy images, (B) particle diameter and (C) zeta potential of the Ad and the CASF/Ad complex. Scale bar: 2.00 μm. CASF 10 to CASF 150 represented the CASF/Ad complexes were formed by coating Ad with CASF at concentrations of 10, 50, 100 ...	00000004	hf://datasets/vector-institute/open-pmc-18m@0d97c202058f2ac1b33438ec35e4b37b31ad3a41/data-000000.tar
{ "caption": "Characteristics of the CASF/Ad complex. (A) Scanning electron microscopy images, (B) particle diameter and (C) zeta potential of the Ad and the CASF/Ad complex. Scale bar: 2.00 μm. CASF 10 to CASF 150 represented the CASF/Ad complexes were formed by coating Ad with CASF at concentrations of 10, 50, 100 ...	00000005	hf://datasets/vector-institute/open-pmc-18m@0d97c202058f2ac1b33438ec35e4b37b31ad3a41/data-000000.tar
{ "caption": "Characteristics of the CASF/Ad complex. (A) Scanning electron microscopy images, (B) particle diameter and (C) zeta potential of the Ad and the CASF/Ad complex. Scale bar: 2.00 μm. CASF 10 to CASF 150 represented the CASF/Ad complexes were formed by coating Ad with CASF at concentrations of 10, 50, 100 ...	00000006	hf://datasets/vector-institute/open-pmc-18m@0d97c202058f2ac1b33438ec35e4b37b31ad3a41/data-000000.tar
{ "caption": "Characteristics of the CASF/Ad complex. (A) Scanning electron microscopy images, (B) particle diameter and (C) zeta potential of the Ad and the CASF/Ad complex. Scale bar: 2.00 μm. CASF 10 to CASF 150 represented the CASF/Ad complexes were formed by coating Ad with CASF at concentrations of 10, 50, 100 ...	00000007	hf://datasets/vector-institute/open-pmc-18m@0d97c202058f2ac1b33438ec35e4b37b31ad3a41/data-000000.tar
{ "caption": "Characteristics of the CASF/Ad complex. (A) Scanning electron microscopy images, (B) particle diameter and (C) zeta potential of the Ad and the CASF/Ad complex. Scale bar: 2.00 μm. CASF 10 to CASF 150 represented the CASF/Ad complexes were formed by coating Ad with CASF at concentrations of 10, 50, 100 ...	00000008	hf://datasets/vector-institute/open-pmc-18m@0d97c202058f2ac1b33438ec35e4b37b31ad3a41/data-000000.tar
{ "caption": "Immunohistochemical staining of PD‐1 and PD‐L1 in primary hepatocellular carcinoma surgical specimens. A,E, PD‐1‐low tumour‐infiltrating lymphocytes; (B,F) PD‐1‐high tumour‐infiltrating lymphocytes; (C,G) PD‐L1‐negative hepatocellular carcinoma; (D,H) PD‐L1‐positive hepatocellular carcinoma; (A‐D, 100× ...	00000009	hf://datasets/vector-institute/open-pmc-18m@0d97c202058f2ac1b33438ec35e4b37b31ad3a41/data-000000.tar
{ "caption": "Immunohistochemical staining of PD‐1 and PD‐L1 in primary hepatocellular carcinoma surgical specimens. A,E, PD‐1‐low tumour‐infiltrating lymphocytes; (B,F) PD‐1‐high tumour‐infiltrating lymphocytes; (C,G) PD‐L1‐negative hepatocellular carcinoma; (D,H) PD‐L1‐positive hepatocellular carcinoma; (A‐D, 100× ...	00000010	hf://datasets/vector-institute/open-pmc-18m@0d97c202058f2ac1b33438ec35e4b37b31ad3a41/data-000000.tar
{ "caption": "Immunohistochemical staining of PD‐1 and PD‐L1 in primary hepatocellular carcinoma surgical specimens. A,E, PD‐1‐low tumour‐infiltrating lymphocytes; (B,F) PD‐1‐high tumour‐infiltrating lymphocytes; (C,G) PD‐L1‐negative hepatocellular carcinoma; (D,H) PD‐L1‐positive hepatocellular carcinoma; (A‐D, 100× ...	00000011	hf://datasets/vector-institute/open-pmc-18m@0d97c202058f2ac1b33438ec35e4b37b31ad3a41/data-000000.tar
{ "caption": "Immunohistochemical staining of PD‐1 and PD‐L1 in primary hepatocellular carcinoma surgical specimens. A,E, PD‐1‐low tumour‐infiltrating lymphocytes; (B,F) PD‐1‐high tumour‐infiltrating lymphocytes; (C,G) PD‐L1‐negative hepatocellular carcinoma; (D,H) PD‐L1‐positive hepatocellular carcinoma; (A‐D, 100× ...	00000012	hf://datasets/vector-institute/open-pmc-18m@0d97c202058f2ac1b33438ec35e4b37b31ad3a41/data-000000.tar
{ "caption": "Immunohistochemical staining of PD‐1 and PD‐L1 in primary hepatocellular carcinoma surgical specimens. A,E, PD‐1‐low tumour‐infiltrating lymphocytes; (B,F) PD‐1‐high tumour‐infiltrating lymphocytes; (C,G) PD‐L1‐negative hepatocellular carcinoma; (D,H) PD‐L1‐positive hepatocellular carcinoma; (A‐D, 100× ...	00000013	hf://datasets/vector-institute/open-pmc-18m@0d97c202058f2ac1b33438ec35e4b37b31ad3a41/data-000000.tar
{ "caption": "Immunohistochemical staining of PD‐1 and PD‐L1 in primary hepatocellular carcinoma surgical specimens. A,E, PD‐1‐low tumour‐infiltrating lymphocytes; (B,F) PD‐1‐high tumour‐infiltrating lymphocytes; (C,G) PD‐L1‐negative hepatocellular carcinoma; (D,H) PD‐L1‐positive hepatocellular carcinoma; (A‐D, 100× ...	00000014	hf://datasets/vector-institute/open-pmc-18m@0d97c202058f2ac1b33438ec35e4b37b31ad3a41/data-000000.tar
{ "caption": "Immunohistochemical staining of PD‐1 and PD‐L1 in primary hepatocellular carcinoma surgical specimens. A,E, PD‐1‐low tumour‐infiltrating lymphocytes; (B,F) PD‐1‐high tumour‐infiltrating lymphocytes; (C,G) PD‐L1‐negative hepatocellular carcinoma; (D,H) PD‐L1‐positive hepatocellular carcinoma; (A‐D, 100× ...	00000015	hf://datasets/vector-institute/open-pmc-18m@0d97c202058f2ac1b33438ec35e4b37b31ad3a41/data-000000.tar
{ "caption": "Immunohistochemical staining of PD‐1 and PD‐L1 in primary hepatocellular carcinoma surgical specimens. A,E, PD‐1‐low tumour‐infiltrating lymphocytes; (B,F) PD‐1‐high tumour‐infiltrating lymphocytes; (C,G) PD‐L1‐negative hepatocellular carcinoma; (D,H) PD‐L1‐positive hepatocellular carcinoma; (A‐D, 100× ...	00000016	hf://datasets/vector-institute/open-pmc-18m@0d97c202058f2ac1b33438ec35e4b37b31ad3a41/data-000000.tar
{ "caption": "Hyperadiponectinemia in chow-fed male offspring of insulin-resistant mothers despite similar adipose histology and gene expression patterns. A: Representative section of gonadal fat, males, aged 6 months. Hematoxylin and eosin staining. Original magnification ×200. B: Gene expression of adipocyte differ...	00000017	hf://datasets/vector-institute/open-pmc-18m@0d97c202058f2ac1b33438ec35e4b37b31ad3a41/data-000000.tar
{ "caption": "Hyperadiponectinemia in chow-fed male offspring of insulin-resistant mothers despite similar adipose histology and gene expression patterns. A: Representative section of gonadal fat, males, aged 6 months. Hematoxylin and eosin staining. Original magnification ×200. B: Gene expression of adipocyte differ...	00000018	hf://datasets/vector-institute/open-pmc-18m@0d97c202058f2ac1b33438ec35e4b37b31ad3a41/data-000000.tar
{ "caption": "Cdk5 regulates sphere formation and tumour establishment.(A) Tumorsphere formation of non-targeting (nt) and Cdk5 shRNA T24 cells is shown (mean±s.e.m., *P<0.05, n=3). Immunoblots of non-targeting (nt) or Cdk5 shRNA-transduced T24 cells for Cdk5 and β-tubulin (loading control) proof Cdk5 knockdown. (B) ...	00000019	hf://datasets/vector-institute/open-pmc-18m@0d97c202058f2ac1b33438ec35e4b37b31ad3a41/data-000000.tar
{ "caption": "Cdk5 regulates sphere formation and tumour establishment.(A) Tumorsphere formation of non-targeting (nt) and Cdk5 shRNA T24 cells is shown (mean±s.e.m., *P<0.05, n=3). Immunoblots of non-targeting (nt) or Cdk5 shRNA-transduced T24 cells for Cdk5 and β-tubulin (loading control) proof Cdk5 knockdown. (B) ...	00000020	hf://datasets/vector-institute/open-pmc-18m@0d97c202058f2ac1b33438ec35e4b37b31ad3a41/data-000000.tar
{ "caption": "Cdk5 regulates sphere formation and tumour establishment.(A) Tumorsphere formation of non-targeting (nt) and Cdk5 shRNA T24 cells is shown (mean±s.e.m., *P<0.05, n=3). Immunoblots of non-targeting (nt) or Cdk5 shRNA-transduced T24 cells for Cdk5 and β-tubulin (loading control) proof Cdk5 knockdown. (B) ...	00000021	hf://datasets/vector-institute/open-pmc-18m@0d97c202058f2ac1b33438ec35e4b37b31ad3a41/data-000000.tar
{ "caption": "Cdk5 regulates sphere formation and tumour establishment.(A) Tumorsphere formation of non-targeting (nt) and Cdk5 shRNA T24 cells is shown (mean±s.e.m., *P<0.05, n=3). Immunoblots of non-targeting (nt) or Cdk5 shRNA-transduced T24 cells for Cdk5 and β-tubulin (loading control) proof Cdk5 knockdown. (B) ...	00000022	hf://datasets/vector-institute/open-pmc-18m@0d97c202058f2ac1b33438ec35e4b37b31ad3a41/data-000000.tar
{ "caption": "Cdk5 regulates sphere formation and tumour establishment.(A) Tumorsphere formation of non-targeting (nt) and Cdk5 shRNA T24 cells is shown (mean±s.e.m., *P<0.05, n=3). Immunoblots of non-targeting (nt) or Cdk5 shRNA-transduced T24 cells for Cdk5 and β-tubulin (loading control) proof Cdk5 knockdown. (B) ...	00000023	hf://datasets/vector-institute/open-pmc-18m@0d97c202058f2ac1b33438ec35e4b37b31ad3a41/data-000000.tar
{ "caption": "Cdk5 regulates sphere formation and tumour establishment.(A) Tumorsphere formation of non-targeting (nt) and Cdk5 shRNA T24 cells is shown (mean±s.e.m., *P<0.05, n=3). Immunoblots of non-targeting (nt) or Cdk5 shRNA-transduced T24 cells for Cdk5 and β-tubulin (loading control) proof Cdk5 knockdown. (B) ...	00000024	hf://datasets/vector-institute/open-pmc-18m@0d97c202058f2ac1b33438ec35e4b37b31ad3a41/data-000000.tar
{ "caption": "Patient 1 renal biopsy tissue stained with (a) hematoxylin and eosin showing a large circumferential cellular crescent, and stained by immunohistochemistry for (b) IgG, (c) IgM, and (d) C3. Indirect immunofluorescence staining of primate kidney sections (Euroimmun, product no FB 1250-1010) incubated ove...	00000025	hf://datasets/vector-institute/open-pmc-18m@0d97c202058f2ac1b33438ec35e4b37b31ad3a41/data-000000.tar
{ "caption": "Patient 1 renal biopsy tissue stained with (a) hematoxylin and eosin showing a large circumferential cellular crescent, and stained by immunohistochemistry for (b) IgG, (c) IgM, and (d) C3. Indirect immunofluorescence staining of primate kidney sections (Euroimmun, product no FB 1250-1010) incubated ove...	00000026	hf://datasets/vector-institute/open-pmc-18m@0d97c202058f2ac1b33438ec35e4b37b31ad3a41/data-000000.tar
{ "caption": "Patient 1 renal biopsy tissue stained with (a) hematoxylin and eosin showing a large circumferential cellular crescent, and stained by immunohistochemistry for (b) IgG, (c) IgM, and (d) C3. Indirect immunofluorescence staining of primate kidney sections (Euroimmun, product no FB 1250-1010) incubated ove...	00000027	hf://datasets/vector-institute/open-pmc-18m@0d97c202058f2ac1b33438ec35e4b37b31ad3a41/data-000000.tar
{ "caption": "Patient 1 renal biopsy tissue stained with (a) hematoxylin and eosin showing a large circumferential cellular crescent, and stained by immunohistochemistry for (b) IgG, (c) IgM, and (d) C3. Indirect immunofluorescence staining of primate kidney sections (Euroimmun, product no FB 1250-1010) incubated ove...	00000028	hf://datasets/vector-institute/open-pmc-18m@0d97c202058f2ac1b33438ec35e4b37b31ad3a41/data-000000.tar
{ "caption": "Patient 1 renal biopsy tissue stained with (a) hematoxylin and eosin showing a large circumferential cellular crescent, and stained by immunohistochemistry for (b) IgG, (c) IgM, and (d) C3. Indirect immunofluorescence staining of primate kidney sections (Euroimmun, product no FB 1250-1010) incubated ove...	00000029	hf://datasets/vector-institute/open-pmc-18m@0d97c202058f2ac1b33438ec35e4b37b31ad3a41/data-000000.tar
{ "caption": "Patient 1 renal biopsy tissue stained with (a) hematoxylin and eosin showing a large circumferential cellular crescent, and stained by immunohistochemistry for (b) IgG, (c) IgM, and (d) C3. Indirect immunofluorescence staining of primate kidney sections (Euroimmun, product no FB 1250-1010) incubated ove...	00000030	hf://datasets/vector-institute/open-pmc-18m@0d97c202058f2ac1b33438ec35e4b37b31ad3a41/data-000000.tar
{ "caption": "Notch signaling increases BMP9-induced late osteogenic differentiation of MSCs. (A) C2C12 cells were treated with different concentrations of DAPT (M=10 μM, and H=15 μM, respectively) in the presence of BMP9-CM, and the gene expression of OCN was determined by semi-quantitative RT-PCR at 7, 9 and 11 day...	00000031	hf://datasets/vector-institute/open-pmc-18m@0d97c202058f2ac1b33438ec35e4b37b31ad3a41/data-000000.tar
{ "caption": "Notch signaling increases BMP9-induced late osteogenic differentiation of MSCs. (A) C2C12 cells were treated with different concentrations of DAPT (M=10 μM, and H=15 μM, respectively) in the presence of BMP9-CM, and the gene expression of OCN was determined by semi-quantitative RT-PCR at 7, 9 and 11 day...	00000032	hf://datasets/vector-institute/open-pmc-18m@0d97c202058f2ac1b33438ec35e4b37b31ad3a41/data-000000.tar
{ "caption": "Notch signaling increases BMP9-induced late osteogenic differentiation of MSCs. (A) C2C12 cells were treated with different concentrations of DAPT (M=10 μM, and H=15 μM, respectively) in the presence of BMP9-CM, and the gene expression of OCN was determined by semi-quantitative RT-PCR at 7, 9 and 11 day...	00000033	hf://datasets/vector-institute/open-pmc-18m@0d97c202058f2ac1b33438ec35e4b37b31ad3a41/data-000000.tar
{ "caption": "Hematoxylin and eosin staining in the (A) G1, (B) G2, (C) G3 and (D) G4 groups. Magnification, ×200. G1 and G3 were the control groups and G2 and G4 were the experimental varicoceles groups. Cells were relatively loose and disordered and the number of vacuoles increased in the G2 and G4 rat groups. G1, ...	00000034	hf://datasets/vector-institute/open-pmc-18m@0d97c202058f2ac1b33438ec35e4b37b31ad3a41/data-000000.tar
{ "caption": "Hematoxylin and eosin staining in the (A) G1, (B) G2, (C) G3 and (D) G4 groups. Magnification, ×200. G1 and G3 were the control groups and G2 and G4 were the experimental varicoceles groups. Cells were relatively loose and disordered and the number of vacuoles increased in the G2 and G4 rat groups. G1, ...	00000035	hf://datasets/vector-institute/open-pmc-18m@0d97c202058f2ac1b33438ec35e4b37b31ad3a41/data-000000.tar
{ "caption": "Hematoxylin and eosin staining in the (A) G1, (B) G2, (C) G3 and (D) G4 groups. Magnification, ×200. G1 and G3 were the control groups and G2 and G4 were the experimental varicoceles groups. Cells were relatively loose and disordered and the number of vacuoles increased in the G2 and G4 rat groups. G1, ...	00000036	hf://datasets/vector-institute/open-pmc-18m@0d97c202058f2ac1b33438ec35e4b37b31ad3a41/data-000000.tar
{ "caption": "Hematoxylin and eosin staining in the (A) G1, (B) G2, (C) G3 and (D) G4 groups. Magnification, ×200. G1 and G3 were the control groups and G2 and G4 were the experimental varicoceles groups. Cells were relatively loose and disordered and the number of vacuoles increased in the G2 and G4 rat groups. G1, ...	00000037	hf://datasets/vector-institute/open-pmc-18m@0d97c202058f2ac1b33438ec35e4b37b31ad3a41/data-000000.tar
{ "caption": "Effect of tunicamycin injection on liver function of ATF6α +/+ and −/− mice. (A) Tunicamycin (Tm) was injected into ATF6α +/+ and −/− mice as described in Figure 1A. Liver tissue sections were prepared at the indicated time points after injection and stained with hematoxylin and eosin. Bar, 100 μm (a–h)...	00000038	hf://datasets/vector-institute/open-pmc-18m@0d97c202058f2ac1b33438ec35e4b37b31ad3a41/data-000000.tar
{ "caption": "Effect of tunicamycin injection on liver function of ATF6α +/+ and −/− mice. (A) Tunicamycin (Tm) was injected into ATF6α +/+ and −/− mice as described in Figure 1A. Liver tissue sections were prepared at the indicated time points after injection and stained with hematoxylin and eosin. Bar, 100 μm (a–h)...	00000039	hf://datasets/vector-institute/open-pmc-18m@0d97c202058f2ac1b33438ec35e4b37b31ad3a41/data-000000.tar
{ "caption": "Effect of tunicamycin injection on liver function of ATF6α +/+ and −/− mice. (A) Tunicamycin (Tm) was injected into ATF6α +/+ and −/− mice as described in Figure 1A. Liver tissue sections were prepared at the indicated time points after injection and stained with hematoxylin and eosin. Bar, 100 μm (a–h)...	00000040	hf://datasets/vector-institute/open-pmc-18m@0d97c202058f2ac1b33438ec35e4b37b31ad3a41/data-000000.tar
{ "caption": "Effect of tunicamycin injection on liver function of ATF6α +/+ and −/− mice. (A) Tunicamycin (Tm) was injected into ATF6α +/+ and −/− mice as described in Figure 1A. Liver tissue sections were prepared at the indicated time points after injection and stained with hematoxylin and eosin. Bar, 100 μm (a–h)...	00000041	hf://datasets/vector-institute/open-pmc-18m@0d97c202058f2ac1b33438ec35e4b37b31ad3a41/data-000000.tar
{ "caption": "Suppression of CMPK2 alleviates I/R-induced deterioration of hepatic injury. (A) Protein detection of CMPK2 in liver tissue. Secretion of (B) IL-18 and (C) IL-1β was measured by ELISA. Hepatocellular function of experimental mice was evaluated by detecting the release of (D) AST and (E) ALT. (F and G) H...	00000042	hf://datasets/vector-institute/open-pmc-18m@0d97c202058f2ac1b33438ec35e4b37b31ad3a41/data-000000.tar
{ "caption": "Suppression of CMPK2 alleviates I/R-induced deterioration of hepatic injury. (A) Protein detection of CMPK2 in liver tissue. Secretion of (B) IL-18 and (C) IL-1β was measured by ELISA. Hepatocellular function of experimental mice was evaluated by detecting the release of (D) AST and (E) ALT. (F and G) H...	00000043	hf://datasets/vector-institute/open-pmc-18m@0d97c202058f2ac1b33438ec35e4b37b31ad3a41/data-000000.tar
{ "caption": "Suppression of CMPK2 alleviates I/R-induced deterioration of hepatic injury. (A) Protein detection of CMPK2 in liver tissue. Secretion of (B) IL-18 and (C) IL-1β was measured by ELISA. Hepatocellular function of experimental mice was evaluated by detecting the release of (D) AST and (E) ALT. (F and G) H...	00000044	hf://datasets/vector-institute/open-pmc-18m@0d97c202058f2ac1b33438ec35e4b37b31ad3a41/data-000000.tar
{ "caption": "Suppression of CMPK2 alleviates I/R-induced deterioration of hepatic injury. (A) Protein detection of CMPK2 in liver tissue. Secretion of (B) IL-18 and (C) IL-1β was measured by ELISA. Hepatocellular function of experimental mice was evaluated by detecting the release of (D) AST and (E) ALT. (F and G) H...	00000045	hf://datasets/vector-institute/open-pmc-18m@0d97c202058f2ac1b33438ec35e4b37b31ad3a41/data-000000.tar
{ "caption": "Localization of Toll-like receptor 2 protein by immunohistochemical analysis in the classical swine fever virus-infected group compared with the uninfected group. Original magnification, ×400.", "primary_modality": "Microscopy", "secondary_modality": "Light microscopy", "source_license": "noncomme...	00000046	hf://datasets/vector-institute/open-pmc-18m@0d97c202058f2ac1b33438ec35e4b37b31ad3a41/data-000000.tar
{ "caption": "Localization of Toll-like receptor 2 protein by immunohistochemical analysis in the classical swine fever virus-infected group compared with the uninfected group. Original magnification, ×400.", "primary_modality": "Microscopy", "secondary_modality": "Light microscopy", "source_license": "noncomme...	00000047	hf://datasets/vector-institute/open-pmc-18m@0d97c202058f2ac1b33438ec35e4b37b31ad3a41/data-000000.tar
{ "caption": "Localization of Toll-like receptor 2 protein by immunohistochemical analysis in the classical swine fever virus-infected group compared with the uninfected group. Original magnification, ×400.", "primary_modality": "Microscopy", "secondary_modality": "Light microscopy", "source_license": "noncomme...	00000048	hf://datasets/vector-institute/open-pmc-18m@0d97c202058f2ac1b33438ec35e4b37b31ad3a41/data-000000.tar
{ "caption": "Localization of Toll-like receptor 2 protein by immunohistochemical analysis in the classical swine fever virus-infected group compared with the uninfected group. Original magnification, ×400.", "primary_modality": "Microscopy", "secondary_modality": "Light microscopy", "source_license": "noncomme...	00000049	hf://datasets/vector-institute/open-pmc-18m@0d97c202058f2ac1b33438ec35e4b37b31ad3a41/data-000000.tar
{ "caption": "Localization of Toll-like receptor 2 protein by immunohistochemical analysis in the classical swine fever virus-infected group compared with the uninfected group. Original magnification, ×400.", "primary_modality": "Microscopy", "secondary_modality": "Light microscopy", "source_license": "noncomme...	00000050	hf://datasets/vector-institute/open-pmc-18m@0d97c202058f2ac1b33438ec35e4b37b31ad3a41/data-000000.tar
{ "caption": "Localization of Toll-like receptor 2 protein by immunohistochemical analysis in the classical swine fever virus-infected group compared with the uninfected group. Original magnification, ×400.", "primary_modality": "Microscopy", "secondary_modality": "Light microscopy", "source_license": "noncomme...	00000051	hf://datasets/vector-institute/open-pmc-18m@0d97c202058f2ac1b33438ec35e4b37b31ad3a41/data-000000.tar
{ "caption": "Localization of Toll-like receptor 2 protein by immunohistochemical analysis in the classical swine fever virus-infected group compared with the uninfected group. Original magnification, ×400.", "primary_modality": "Microscopy", "secondary_modality": "Light microscopy", "source_license": "noncomme...	00000052	hf://datasets/vector-institute/open-pmc-18m@0d97c202058f2ac1b33438ec35e4b37b31ad3a41/data-000000.tar
{ "caption": "Localization of Toll-like receptor 2 protein by immunohistochemical analysis in the classical swine fever virus-infected group compared with the uninfected group. Original magnification, ×400.", "primary_modality": "Microscopy", "secondary_modality": "Light microscopy", "source_license": "noncomme...	00000053	hf://datasets/vector-institute/open-pmc-18m@0d97c202058f2ac1b33438ec35e4b37b31ad3a41/data-000000.tar
{ "caption": "Localization of Toll-like receptor 2 protein by immunohistochemical analysis in the classical swine fever virus-infected group compared with the uninfected group. Original magnification, ×400.", "primary_modality": "Microscopy", "secondary_modality": "Light microscopy", "source_license": "noncomme...	00000054	hf://datasets/vector-institute/open-pmc-18m@0d97c202058f2ac1b33438ec35e4b37b31ad3a41/data-000000.tar
{ "caption": "Localization of Toll-like receptor 2 protein by immunohistochemical analysis in the classical swine fever virus-infected group compared with the uninfected group. Original magnification, ×400.", "primary_modality": "Microscopy", "secondary_modality": "Light microscopy", "source_license": "noncomme...	00000055	hf://datasets/vector-institute/open-pmc-18m@0d97c202058f2ac1b33438ec35e4b37b31ad3a41/data-000000.tar
{ "caption": "Effects of Wnt5a on the melanogenesis of melan-a cells. (A) Tyrosinase activity of melan-a cells infected with different doses of AdWnt5a or AdGFP analyzed by tyrosinase activity assay. (B) Melanin synthesis of melan-a cells infected with AdWnt5a or AdGFP. (C-D) Effect of Wnt5a on the expression of TRP1...	00000056	hf://datasets/vector-institute/open-pmc-18m@0d97c202058f2ac1b33438ec35e4b37b31ad3a41/data-000000.tar
{ "caption": "Effects of Wnt5a on the melanogenesis of melan-a cells. (A) Tyrosinase activity of melan-a cells infected with different doses of AdWnt5a or AdGFP analyzed by tyrosinase activity assay. (B) Melanin synthesis of melan-a cells infected with AdWnt5a or AdGFP. (C-D) Effect of Wnt5a on the expression of TRP1...	00000057	hf://datasets/vector-institute/open-pmc-18m@0d97c202058f2ac1b33438ec35e4b37b31ad3a41/data-000000.tar
{ "caption": "Tamoxifen inhibits HO at different phases of progression. (A) Representative imageological examination of Achilles tendons by μCT. (B) Quantitation of BV at different groups. (C) H&E staining of Achilles tendons. (D, E) Representative immunohistochemical staining and quantitative analysis of Ocn-positiv...	00000058	hf://datasets/vector-institute/open-pmc-18m@0d97c202058f2ac1b33438ec35e4b37b31ad3a41/data-000000.tar
{ "caption": "Tamoxifen inhibits HO at different phases of progression. (A) Representative imageological examination of Achilles tendons by μCT. (B) Quantitation of BV at different groups. (C) H&E staining of Achilles tendons. (D, E) Representative immunohistochemical staining and quantitative analysis of Ocn-positiv...	00000059	hf://datasets/vector-institute/open-pmc-18m@0d97c202058f2ac1b33438ec35e4b37b31ad3a41/data-000000.tar
{ "caption": "Tamoxifen inhibits HO at different phases of progression. (A) Representative imageological examination of Achilles tendons by μCT. (B) Quantitation of BV at different groups. (C) H&E staining of Achilles tendons. (D, E) Representative immunohistochemical staining and quantitative analysis of Ocn-positiv...	00000060	hf://datasets/vector-institute/open-pmc-18m@0d97c202058f2ac1b33438ec35e4b37b31ad3a41/data-000000.tar
{ "caption": "Tamoxifen inhibits HO at different phases of progression. (A) Representative imageological examination of Achilles tendons by μCT. (B) Quantitation of BV at different groups. (C) H&E staining of Achilles tendons. (D, E) Representative immunohistochemical staining and quantitative analysis of Ocn-positiv...	00000061	hf://datasets/vector-institute/open-pmc-18m@0d97c202058f2ac1b33438ec35e4b37b31ad3a41/data-000000.tar
{ "caption": "Tamoxifen inhibits HO at different phases of progression. (A) Representative imageological examination of Achilles tendons by μCT. (B) Quantitation of BV at different groups. (C) H&E staining of Achilles tendons. (D, E) Representative immunohistochemical staining and quantitative analysis of Ocn-positiv...	00000062	hf://datasets/vector-institute/open-pmc-18m@0d97c202058f2ac1b33438ec35e4b37b31ad3a41/data-000000.tar
{ "caption": "Tamoxifen inhibits HO at different phases of progression. (A) Representative imageological examination of Achilles tendons by μCT. (B) Quantitation of BV at different groups. (C) H&E staining of Achilles tendons. (D, E) Representative immunohistochemical staining and quantitative analysis of Ocn-positiv...	00000063	hf://datasets/vector-institute/open-pmc-18m@0d97c202058f2ac1b33438ec35e4b37b31ad3a41/data-000000.tar
{ "caption": "Tamoxifen inhibits HO at different phases of progression. (A) Representative imageological examination of Achilles tendons by μCT. (B) Quantitation of BV at different groups. (C) H&E staining of Achilles tendons. (D, E) Representative immunohistochemical staining and quantitative analysis of Ocn-positiv...	00000064	hf://datasets/vector-institute/open-pmc-18m@0d97c202058f2ac1b33438ec35e4b37b31ad3a41/data-000000.tar
{ "caption": "Tamoxifen inhibits HO at different phases of progression. (A) Representative imageological examination of Achilles tendons by μCT. (B) Quantitation of BV at different groups. (C) H&E staining of Achilles tendons. (D, E) Representative immunohistochemical staining and quantitative analysis of Ocn-positiv...	00000065	hf://datasets/vector-institute/open-pmc-18m@0d97c202058f2ac1b33438ec35e4b37b31ad3a41/data-000000.tar
{ "caption": "Tamoxifen inhibits HO at different phases of progression. (A) Representative imageological examination of Achilles tendons by μCT. (B) Quantitation of BV at different groups. (C) H&E staining of Achilles tendons. (D, E) Representative immunohistochemical staining and quantitative analysis of Ocn-positiv...	00000066	hf://datasets/vector-institute/open-pmc-18m@0d97c202058f2ac1b33438ec35e4b37b31ad3a41/data-000000.tar
{ "caption": "Tamoxifen inhibits HO at different phases of progression. (A) Representative imageological examination of Achilles tendons by μCT. (B) Quantitation of BV at different groups. (C) H&E staining of Achilles tendons. (D, E) Representative immunohistochemical staining and quantitative analysis of Ocn-positiv...	00000067	hf://datasets/vector-institute/open-pmc-18m@0d97c202058f2ac1b33438ec35e4b37b31ad3a41/data-000000.tar
{ "caption": "Tamoxifen inhibits HO at different phases of progression. (A) Representative imageological examination of Achilles tendons by μCT. (B) Quantitation of BV at different groups. (C) H&E staining of Achilles tendons. (D, E) Representative immunohistochemical staining and quantitative analysis of Ocn-positiv...	00000068	hf://datasets/vector-institute/open-pmc-18m@0d97c202058f2ac1b33438ec35e4b37b31ad3a41/data-000000.tar
{ "caption": "Pyrrolidine dithiocarbamate (PDTC) reduced myocardial injury and pyroptosis in coronary microembolization (CME) rats. (A) Myocardial tissue structural injury of rats in the CME + PDTC group observed by haematoxylin and eosin (HE) and basic fuchsin picric acid (HBFP) staining. (B,C,D) The expression of (...	00000069	hf://datasets/vector-institute/open-pmc-18m@0d97c202058f2ac1b33438ec35e4b37b31ad3a41/data-000000.tar
{ "caption": "The nuclear factor‐kappa B (NF‐κB) signalling pathway and pyroptosis were activated in myocardial tissues of coronary microembolization (CME) rats. (A) Protein levels of NF‐κB p65, NLRP3, DSDMD, and caspase‐1 measured by Western blot analysis. (B,C) Expressions of IL‐1β and IL‐18 in myocardial tissues o...	00000070	hf://datasets/vector-institute/open-pmc-18m@0d97c202058f2ac1b33438ec35e4b37b31ad3a41/data-000000.tar
{ "caption": "Liver biopsy histopathology revealing signs of HH. H&E-stained sections (left column) showing preservation of the hepatic lobular structure and many tan pigment granules in the cytoplasm. Masson-stained sections (center column) showing subcutaneous fibrosis in the central vein and occasional bridging fi...	00000071	hf://datasets/vector-institute/open-pmc-18m@0d97c202058f2ac1b33438ec35e4b37b31ad3a41/data-000000.tar
{ "caption": "Liver biopsy histopathology revealing signs of HH. H&E-stained sections (left column) showing preservation of the hepatic lobular structure and many tan pigment granules in the cytoplasm. Masson-stained sections (center column) showing subcutaneous fibrosis in the central vein and occasional bridging fi...	00000072	hf://datasets/vector-institute/open-pmc-18m@0d97c202058f2ac1b33438ec35e4b37b31ad3a41/data-000000.tar
{ "caption": "Liver biopsy histopathology revealing signs of HH. H&E-stained sections (left column) showing preservation of the hepatic lobular structure and many tan pigment granules in the cytoplasm. Masson-stained sections (center column) showing subcutaneous fibrosis in the central vein and occasional bridging fi...	00000073	hf://datasets/vector-institute/open-pmc-18m@0d97c202058f2ac1b33438ec35e4b37b31ad3a41/data-000000.tar
{ "caption": "Liver biopsy histopathology revealing signs of HH. H&E-stained sections (left column) showing preservation of the hepatic lobular structure and many tan pigment granules in the cytoplasm. Masson-stained sections (center column) showing subcutaneous fibrosis in the central vein and occasional bridging fi...	00000074	hf://datasets/vector-institute/open-pmc-18m@0d97c202058f2ac1b33438ec35e4b37b31ad3a41/data-000000.tar
{ "caption": "Liver biopsy histopathology revealing signs of HH. H&E-stained sections (left column) showing preservation of the hepatic lobular structure and many tan pigment granules in the cytoplasm. Masson-stained sections (center column) showing subcutaneous fibrosis in the central vein and occasional bridging fi...	00000075	hf://datasets/vector-institute/open-pmc-18m@0d97c202058f2ac1b33438ec35e4b37b31ad3a41/data-000000.tar
{ "caption": "Liver biopsy histopathology revealing signs of HH. H&E-stained sections (left column) showing preservation of the hepatic lobular structure and many tan pigment granules in the cytoplasm. Masson-stained sections (center column) showing subcutaneous fibrosis in the central vein and occasional bridging fi...	00000076	hf://datasets/vector-institute/open-pmc-18m@0d97c202058f2ac1b33438ec35e4b37b31ad3a41/data-000000.tar
{ "caption": "Liver biopsy histopathology revealing signs of HH. H&E-stained sections (left column) showing preservation of the hepatic lobular structure and many tan pigment granules in the cytoplasm. Masson-stained sections (center column) showing subcutaneous fibrosis in the central vein and occasional bridging fi...	00000077	hf://datasets/vector-institute/open-pmc-18m@0d97c202058f2ac1b33438ec35e4b37b31ad3a41/data-000000.tar
{ "caption": "Liver biopsy histopathology revealing signs of HH. H&E-stained sections (left column) showing preservation of the hepatic lobular structure and many tan pigment granules in the cytoplasm. Masson-stained sections (center column) showing subcutaneous fibrosis in the central vein and occasional bridging fi...	00000078	hf://datasets/vector-institute/open-pmc-18m@0d97c202058f2ac1b33438ec35e4b37b31ad3a41/data-000000.tar
{ "caption": "Liver biopsy histopathology revealing signs of HH. H&E-stained sections (left column) showing preservation of the hepatic lobular structure and many tan pigment granules in the cytoplasm. Masson-stained sections (center column) showing subcutaneous fibrosis in the central vein and occasional bridging fi...	00000079	hf://datasets/vector-institute/open-pmc-18m@0d97c202058f2ac1b33438ec35e4b37b31ad3a41/data-000000.tar
{ "caption": "Migratory process of PC cells was inhibited by miR-361. Migration of transfected (A) PANC-1 and (B) AsPC-1 cells was measured via wound-healing assay. Magnification, x40. Migration of (C) PANC-1 and (D) AsPC-1 cells was also measured using a Transwell migration assay following transfection with miR-361 ...	00000080	hf://datasets/vector-institute/open-pmc-18m@0d97c202058f2ac1b33438ec35e4b37b31ad3a41/data-000000.tar
{ "caption": "Migratory process of PC cells was inhibited by miR-361. Migration of transfected (A) PANC-1 and (B) AsPC-1 cells was measured via wound-healing assay. Magnification, x40. Migration of (C) PANC-1 and (D) AsPC-1 cells was also measured using a Transwell migration assay following transfection with miR-361 ...	00000081	hf://datasets/vector-institute/open-pmc-18m@0d97c202058f2ac1b33438ec35e4b37b31ad3a41/data-000000.tar
{ "caption": "Migratory process of PC cells was inhibited by miR-361. Migration of transfected (A) PANC-1 and (B) AsPC-1 cells was measured via wound-healing assay. Magnification, x40. Migration of (C) PANC-1 and (D) AsPC-1 cells was also measured using a Transwell migration assay following transfection with miR-361 ...	00000082	hf://datasets/vector-institute/open-pmc-18m@0d97c202058f2ac1b33438ec35e4b37b31ad3a41/data-000000.tar
{ "caption": "Effects of PCs on MPTP-induced apoptosis. (A) A TUNEL assay was performed to detect apoptosis, and TUNEL-positive cells were detected (magnification, ×200). (B) ROS levels were measured using the fluorescent probe, 2′,7′-dichlorodihydrofluorescein diacetate. (C) JNK/c-Jun signaling pathway proteins were...	00000083	hf://datasets/vector-institute/open-pmc-18m@0d97c202058f2ac1b33438ec35e4b37b31ad3a41/data-000000.tar
{ "caption": "Effects of PCs on MPTP-induced apoptosis. (A) A TUNEL assay was performed to detect apoptosis, and TUNEL-positive cells were detected (magnification, ×200). (B) ROS levels were measured using the fluorescent probe, 2′,7′-dichlorodihydrofluorescein diacetate. (C) JNK/c-Jun signaling pathway proteins were...	00000084	hf://datasets/vector-institute/open-pmc-18m@0d97c202058f2ac1b33438ec35e4b37b31ad3a41/data-000000.tar
{ "caption": "Effects of PCs on MPTP-induced apoptosis. (A) A TUNEL assay was performed to detect apoptosis, and TUNEL-positive cells were detected (magnification, ×200). (B) ROS levels were measured using the fluorescent probe, 2′,7′-dichlorodihydrofluorescein diacetate. (C) JNK/c-Jun signaling pathway proteins were...	00000085	hf://datasets/vector-institute/open-pmc-18m@0d97c202058f2ac1b33438ec35e4b37b31ad3a41/data-000000.tar
{ "caption": "Effects of PCs on MPTP-induced apoptosis. (A) A TUNEL assay was performed to detect apoptosis, and TUNEL-positive cells were detected (magnification, ×200). (B) ROS levels were measured using the fluorescent probe, 2′,7′-dichlorodihydrofluorescein diacetate. (C) JNK/c-Jun signaling pathway proteins were...	00000086	hf://datasets/vector-institute/open-pmc-18m@0d97c202058f2ac1b33438ec35e4b37b31ad3a41/data-000000.tar
{ "caption": "Effects of PCs on MPTP-induced apoptosis. (A) A TUNEL assay was performed to detect apoptosis, and TUNEL-positive cells were detected (magnification, ×200). (B) ROS levels were measured using the fluorescent probe, 2′,7′-dichlorodihydrofluorescein diacetate. (C) JNK/c-Jun signaling pathway proteins were...	00000087	hf://datasets/vector-institute/open-pmc-18m@0d97c202058f2ac1b33438ec35e4b37b31ad3a41/data-000000.tar
{ "caption": "CCR4−/− T reg cells fail to prevent cutaneous and pulmonary inflammation after transfer into neonatal sf mice. Photomicrographs of hematoxylin and eosin–stained sections of skin, lung, and liver from either an unmanipulated sf mouse (bottom) or from sf mice given purified WT or CCR4−/− CD4+CD25+ T reg c...	00000088	hf://datasets/vector-institute/open-pmc-18m@0d97c202058f2ac1b33438ec35e4b37b31ad3a41/data-000000.tar
{ "caption": "CCR4−/− T reg cells fail to prevent cutaneous and pulmonary inflammation after transfer into neonatal sf mice. Photomicrographs of hematoxylin and eosin–stained sections of skin, lung, and liver from either an unmanipulated sf mouse (bottom) or from sf mice given purified WT or CCR4−/− CD4+CD25+ T reg c...	00000089	hf://datasets/vector-institute/open-pmc-18m@0d97c202058f2ac1b33438ec35e4b37b31ad3a41/data-000000.tar
{ "caption": "CCR4−/− T reg cells fail to prevent cutaneous and pulmonary inflammation after transfer into neonatal sf mice. Photomicrographs of hematoxylin and eosin–stained sections of skin, lung, and liver from either an unmanipulated sf mouse (bottom) or from sf mice given purified WT or CCR4−/− CD4+CD25+ T reg c...	00000090	hf://datasets/vector-institute/open-pmc-18m@0d97c202058f2ac1b33438ec35e4b37b31ad3a41/data-000000.tar
{ "caption": "CCR4−/− T reg cells fail to prevent cutaneous and pulmonary inflammation after transfer into neonatal sf mice. Photomicrographs of hematoxylin and eosin–stained sections of skin, lung, and liver from either an unmanipulated sf mouse (bottom) or from sf mice given purified WT or CCR4−/− CD4+CD25+ T reg c...	00000091	hf://datasets/vector-institute/open-pmc-18m@0d97c202058f2ac1b33438ec35e4b37b31ad3a41/data-000000.tar
{ "caption": "CCR4−/− T reg cells fail to prevent cutaneous and pulmonary inflammation after transfer into neonatal sf mice. Photomicrographs of hematoxylin and eosin–stained sections of skin, lung, and liver from either an unmanipulated sf mouse (bottom) or from sf mice given purified WT or CCR4−/− CD4+CD25+ T reg c...	00000092	hf://datasets/vector-institute/open-pmc-18m@0d97c202058f2ac1b33438ec35e4b37b31ad3a41/data-000000.tar
{ "caption": "CCR4−/− T reg cells fail to prevent cutaneous and pulmonary inflammation after transfer into neonatal sf mice. Photomicrographs of hematoxylin and eosin–stained sections of skin, lung, and liver from either an unmanipulated sf mouse (bottom) or from sf mice given purified WT or CCR4−/− CD4+CD25+ T reg c...	00000093	hf://datasets/vector-institute/open-pmc-18m@0d97c202058f2ac1b33438ec35e4b37b31ad3a41/data-000000.tar
{ "caption": "CCR4−/− T reg cells fail to prevent cutaneous and pulmonary inflammation after transfer into neonatal sf mice. Photomicrographs of hematoxylin and eosin–stained sections of skin, lung, and liver from either an unmanipulated sf mouse (bottom) or from sf mice given purified WT or CCR4−/− CD4+CD25+ T reg c...	00000094	hf://datasets/vector-institute/open-pmc-18m@0d97c202058f2ac1b33438ec35e4b37b31ad3a41/data-000000.tar
{ "caption": "CCR4−/− T reg cells fail to prevent cutaneous and pulmonary inflammation after transfer into neonatal sf mice. Photomicrographs of hematoxylin and eosin–stained sections of skin, lung, and liver from either an unmanipulated sf mouse (bottom) or from sf mice given purified WT or CCR4−/− CD4+CD25+ T reg c...	00000095	hf://datasets/vector-institute/open-pmc-18m@0d97c202058f2ac1b33438ec35e4b37b31ad3a41/data-000000.tar
{ "caption": "CCR4−/− T reg cells fail to prevent cutaneous and pulmonary inflammation after transfer into neonatal sf mice. Photomicrographs of hematoxylin and eosin–stained sections of skin, lung, and liver from either an unmanipulated sf mouse (bottom) or from sf mice given purified WT or CCR4−/− CD4+CD25+ T reg c...	00000096	hf://datasets/vector-institute/open-pmc-18m@0d97c202058f2ac1b33438ec35e4b37b31ad3a41/data-000000.tar
{ "caption": "Minocycline alleviated LPS-induced myocardial injury in mice. (A) Heart tissues were stained with H&E solution to elucidate pathological alterations. (B,C) The serum concentration of creatine kinase-MB (CK-MB) and lactate dehydrogenase (LDH) were detected. (D–F) The expression levels of Bax and Bcl-2 in...	00000097	hf://datasets/vector-institute/open-pmc-18m@0d97c202058f2ac1b33438ec35e4b37b31ad3a41/data-000000.tar
{ "caption": "Minocycline alleviated LPS-induced myocardial injury in mice. (A) Heart tissues were stained with H&E solution to elucidate pathological alterations. (B,C) The serum concentration of creatine kinase-MB (CK-MB) and lactate dehydrogenase (LDH) were detected. (D–F) The expression levels of Bax and Bcl-2 in...	00000098	hf://datasets/vector-institute/open-pmc-18m@0d97c202058f2ac1b33438ec35e4b37b31ad3a41/data-000000.tar
{ "caption": "Minocycline alleviated LPS-induced myocardial injury in mice. (A) Heart tissues were stained with H&E solution to elucidate pathological alterations. (B,C) The serum concentration of creatine kinase-MB (CK-MB) and lactate dehydrogenase (LDH) were detected. (D–F) The expression levels of Bax and Bcl-2 in...	00000099	hf://datasets/vector-institute/open-pmc-18m@0d97c202058f2ac1b33438ec35e4b37b31ad3a41/data-000000.tar

End of preview. Expand in Data Studio

OPEN-PMC

Arxiv: Arxiv | Code: Open-PMC Github | Model Checkpoint: Hugging Face

Dataset Summary

This dataset consists of image-text pairs extracted from medical papers available on PubMed Central. It has been curated to support research in medical image understanding, particularly in natural language processing (NLP) and computer vision tasks related to medical imagery. The dataset includes:

Extracted images from research articles.
Associated captions and sub-captions with each image.
All pairs are filtered medical image-text pairs.
All images are decomposed compound figures with their respective sub-captions.
Summarized in-text references to corresponding images for better model training.

Supported Tasks and Benchmarks

This dataset is designed for research in:

Medical Image Captioning: Training and evaluating models that generate descriptions for medical images.
Multimodal Learning: Studying the relationship between medical images and their textual descriptions.
Image-Text Retrieval: Enabling models to retrieve relevant images based on textual queries and vice versa.
Medical Language Understanding: Assisting in understanding complex medical terminology in images.

Languages

The dataset primarily contains text in English.

Dataset Structure

Data Fields

Each record in the dataset contains:

Image: Filename of each extracted and decomposed image.
Full caption: Original figure caption from the research paper.

Data Splits

The dataset does not contain predefined splits. Users can split the data as needed for training, validation, and testing.

Dataset Creation

Source Data

Initial Data Collection and Processing

Data Collection: We used the raw data provided in BIOMEDICA.
Filtering: Non-medical image-text pairs were removed to ensure a focused dataset.
Compound Figure Decomposition: Multi-panel figures were split into individual sub-figures.

Annotations

The dataset does not contain additional manual annotations.

Uses

This dataset is designed for research purposes only and should not be used for:

Clinical diagnosis.
Medical decision-making.
Any real-world patient care applications.

Ethical Considerations

This dataset is derived from open-access publications available on PubMed Central.
Researchers should comply with ethical guidelines and ensure that their work does not imply clinical utility.
The dataset is intended strictly for academic and research purposes.

Citation

If you find the code useful for your research, please consider citing

@article{baghbanzadeh2025open,
  title={Open-PMC-18M: A High-Fidelity Large Scale Medical Dataset for Multimodal Representation Learning},
  author={Baghbanzadeh, Negin and Ashkezari, Sajad and Dolatabadi, Elham and Afkanpour, Arash},
  journal={arXiv preprint arXiv:2506.02738},
  year={2025}
}