query
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173
| query_id
stringlengths 12
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25
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listlengths 1
29
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|---|---|---|---|---|
What are the specific outcomes of using autologous chondrocyte implantation in canine studies?
|
query-test-0
|
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[
"27",
"29",
"36",
"28"
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How does a healthy knee joint differ from a total knee replacement prosthesis in terms of materials used?
|
query-test-1
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[
"1"
] |
What is the regeneration potential of bone compared to other joint tissues?
|
query-test-2
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[
"5"
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What are the challenges in regenerating joint tissues due to the intraarticular joint environment?
|
query-test-3
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[
"3",
"4"
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What are the current and future clinical practices for cartilage regeneration?
|
query-test-4
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"33",
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How do the characteristics of articular cartilage compare to those of the meniscus?
|
query-test-5
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[
"6",
"5"
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What does the graph on subchondral bone densification in sheep studies indicate?
|
query-test-6
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[
"17"
] |
What insights can be drawn from the histological images comparing different treatment groups in cartilage regeneration studies?
|
query-test-7
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[
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How do the cell types and vascularity of articular cartilage and ACL differ?
|
query-test-8
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[
"6"
] |
What are the specific challenges faced by ligament devices in orthopaedic applications?
|
query-test-9
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[
"113",
"114",
"118",
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What role do biomaterials play in the development of joint replacement prostheses?
|
query-test-10
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[
"57",
"119"
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What are the potential impacts of mechanical loading on dental implants?
|
query-test-11
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[
"91"
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What insights can be gained from figures illustrating the mechanical loading of teeth?
|
query-test-12
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[
"64"
] |
What are the specific roles of ECMs in cellular processes that cannot be derived from the document?
|
query-test-13
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[
"125"
] |
What is the primary structural feature of collagen that contributes to its helical formation?
|
query-test-14
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[
"132"
] |
How do ECMs contribute to the positional homeostasis of organs within animals?
|
query-test-15
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[
"126"
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How do the roles of integrins in cell-matrix interactions compare to their roles in signal transmission within the cell?
|
query-test-16
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[
"154"
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What is the significance of the glycine 'hinge' in the primary structure of collagen?
|
query-test-17
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[
"132"
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How do tissue engineering and regenerative medicine differ in their approach to healing damaged tissues?
|
query-test-18
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[
"162",
"163"
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What role do scaffolds play in tissue engineering?
|
query-test-19
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[
"162",
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In what ways do autologous and allogeneic cells differ in their application to tissue engineering?
|
query-test-20
|
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501,
164,
160,
502,
168,
161,
864,
504,
690,
20,
19,
889,
27,
167,
173
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[
0.6181640625,
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[
"174"
] |
What types of tissues are unable to regenerate spontaneously?
|
query-test-21
|
[
503,
176,
767,
847,
969,
768,
690,
164,
661,
160,
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[
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[
"179",
"176"
] |
What are the key factors illustrated in the figures that contribute to successful tissue engineering?
|
query-test-22
|
[
896,
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[
"172",
"165",
"166",
"178",
"167",
"181",
"179",
"173",
"159",
"180"
] |
What are some potential challenges in achieving successful tissue integration with biomaterials?
|
query-test-23
|
[
194,
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[
"193",
"190"
] |
What factors influence the bonding of bone to implants?
|
query-test-24
|
[
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[
"194",
"216",
"214"
] |
What does a microscopic image reveal about the interaction between implants and bone tissue at a specific time point post-implantation?
|
query-test-25
|
[
208,
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[
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"221",
"206",
"208",
"219",
"211",
"205",
"218",
"207",
"215"
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What insights can be drawn about the long-term effects of implants on surrounding tissue from the diagrams?
|
query-test-26
|
[
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[
"223",
"192",
"193",
"185",
"190"
] |
How do the diagrams explain the process of osseointegration in dental implants?
|
query-test-27
|
[
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[
"210",
"207",
"208"
] |
What are the differences in tissue response between two types of implant materials as shown in the tables?
|
query-test-28
|
[
193,
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277,
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[
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0.384765625,
0.384765625
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[
"213"
] |
What is the role of glycosaminoglycans in maintaining cartilage stiffness?
|
query-test-29
|
[
270,
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252,
229,
271,
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[
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[
"270",
"269"
] |
What are the fundamental principles of linear elastic mechanics as they apply to tissue deformability?
|
query-test-30
|
[
227,
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479,
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271,
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861,
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[
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0.33642578125,
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[
"227"
] |
What does the electron microscope photograph reveal about the structure of collagen fibers in the cornea?
|
query-test-31
|
[
652,
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813,
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234,
874,
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892,
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718,
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[
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[
"239"
] |
In what ways might the amorphous nature of elastin fibers contribute to their mechanical properties?
|
query-test-32
|
[
265,
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144,
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[
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[
"265"
] |
What insights do the diagrams provide about the quaternary structure of collagen and its periodicity?
|
query-test-33
|
[
874,
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[
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0.37841796875,
0.37841796875
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[
"232",
"260"
] |
What is the primary function of endothelial cells in wound healing?
|
query-test-34
|
[
988,
973,
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275,
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661,
630,
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[
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[
"284"
] |
How might the diagrams illustrate the interaction between different cell types during wound healing?
|
query-test-35
|
[
640,
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972,
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276,
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[
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[
"280",
"297",
"298",
"300",
"276",
"304",
"277"
] |
What insights do the diagrams provide about the synthesis of new collagen in wound healing?
|
query-test-36
|
[
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[
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[
"304",
"300",
"277",
"303"
] |
How do the roles of macrophages and endothelial cells compare in the tables related to wound healing processes?
|
query-test-37
|
[
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526,
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[
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0.35498046875,
0.353515625
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[
"297"
] |
How do fibroblast and prostate cancer cell migration speeds differ on collagen-GAG scaffolds?
|
query-test-38
|
[
312,
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311,
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[
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[
"312"
] |
What role do integrins play in the adhesion processes of cancer cells?
|
query-test-39
|
[
315,
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409,
316,
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403,
400,
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[
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0.40087890625,
0.3896484375
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[
"316",
"315"
] |
How might environmental factors influence the observable traits of an organism?
|
query-test-40
|
[
307,
479,
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228,
681,
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239,
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[
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What are the implications of scaffold pore size on skin wound contraction and regeneration?
|
query-test-41
|
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[
"317"
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What happens to fibroblast migration speed as the average pore size of collagen-GAG scaffolds increases?
|
query-test-42
|
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[
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In what ways could scaffold properties potentially affect cancer cell proliferation and metastasis?
|
query-test-43
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[
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What is the primary advantage of using two-photon microscopy for quantifying ligand density?
|
query-test-44
|
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How does the proposed methodology enhance the study of collagen-GAG scaffolds?
|
query-test-45
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[
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What are the differences in results obtained from two-photon microscopy and confocal microscopy?
|
query-test-46
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What specific biological mechanism is highlighted in the study of collagen-GAG scaffolds?
|
query-test-47
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[
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How might the visualization of free and bound ligands impact future biomaterial research?
|
query-test-48
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[
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What qualitative insights can be drawn from the figures illustrating ligand density measurements?
|
query-test-49
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[
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In what ways do the ligand density values for different biomaterials compare in the tables?
|
query-test-50
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[
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What is the exact mathematical formula used to describe the sigma-shaped curves in ligand adsorption?
|
query-test-51
|
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[
"331",
"330"
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What role does stochastic independence play in ligand adsorption onto biomaterial surfaces?
|
query-test-52
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[
"330"
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How does the document describe the transition from noncooperative to cooperative cell behavior?
|
query-test-53
|
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[
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What information does the document provide about the diffusion of regulators inside and outside a control volume?
|
query-test-54
|
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[
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What insights can be drawn about the communication between cells during the critical transition to cooperative behavior?
|
query-test-55
|
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[
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What are the similarities and differences between the two special cases analyzed in the mathematical model of cell behavior transition?
|
query-test-56
|
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[
"335",
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What is the exact percentage increase in nerve regeneration success when using a specific tube material compared to another?
|
query-test-57
|
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[
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How does the structure of myelinated axons compare to the structure of the endoneurium in peripheral nerves?
|
query-test-58
|
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[
"351",
"353"
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What are the key experimental parameters for studying nerve regeneration mentioned in the document?
|
query-test-59
|
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[
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How does the presence of a tube influence the process of nerve regeneration?
|
query-test-60
|
[
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[
"384",
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What are the differences in regenerative activity between various tube wall compositions used in nerve regeneration experiments?
|
query-test-61
|
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[
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What is the observed effect of tube wall permeability on nerve regeneration quality?
|
query-test-62
|
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[
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What insights can be drawn about the role of tube fillings in nerve regeneration from the experimental data?
|
query-test-63
|
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[
"384",
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How do the diagrams and microscopy images contribute to understanding the anatomy of peripheral nerves?
|
query-test-64
|
[
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[
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"350",
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In terms of axon elongation, how do different tube materials compare in their effectiveness?
|
query-test-65
|
[
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[
"384",
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How do integrins differ in their roles in cell-matrix adhesion compared to cell-cell adhesion?
|
query-test-66
|
[
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[
"402"
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What is the significance of the RGD amino acid sequence in adhesion proteins?
|
query-test-67
|
[
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[
"403"
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How might integrins influence cellular behavior in different environments?
|
query-test-68
|
[
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[
"409"
] |
What are the key functions of integrins in cell motility and adhesion?
|
query-test-69
|
[
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[
"409"
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What does the diagram reveal about the interaction between integrins and extracellular matrix components?
|
query-test-70
|
[
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[
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[
"408",
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"410",
"401",
"407",
"404",
"400",
"402"
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How do integrins contribute to the structural integrity of cells as shown in the figures?
|
query-test-71
|
[
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[
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[
"409",
"403",
"410",
"404",
"402"
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What was the outcome of using collagen-glycosaminoglycan membranes seeded with autologous keratinocytes on porcine wounds?
|
query-test-72
|
[
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[
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[
"437"
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How does the application of autologous keratinocytes contribute to the process of epithelialization and epidermal regeneration?
|
query-test-73
|
[
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[
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[
"437"
] |
What is the minimum cell density required for keratinocytes to form a confluent epidermis on collagen-glycosaminoglycan matrices?
|
query-test-74
|
[
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779,
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[
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[
"437"
] |
What are the specific patency rates for different types of vascular prostheses?
|
query-test-75
|
[
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[
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0.29345703125,
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[
"461"
] |
What is the primary challenge in creating successful vascular grafts for small-diameter vessels?
|
query-test-76
|
[
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[
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[
"471",
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"482",
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What are the potential future advancements in vascular prostheses based on current challenges?
|
query-test-77
|
[
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[
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[
"441"
] |
How have historical perspectives influenced the development of vascular implants?
|
query-test-78
|
[
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[
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[
"463",
"466",
"464",
"465"
] |
What is the compliance rate of a specific material used in vascular prostheses?
|
query-test-79
|
[
480,
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[
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[
"480"
] |
What are the implications of compliance mismatch in vascular prostheses on patient outcomes?
|
query-test-80
|
[
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484,
458,
457,
480,
485,
468,
477,
474,
472,
470,
489,
483,
460,
476,
119,
57,
876,
509,
479,
118,
471
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[
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0.36328125,
0.36279296875,
0.357421875
] |
[
"459"
] |
How do mechanical factors influence the success of vascular grafts?
|
query-test-81
|
[
485,
484,
483,
479,
478,
468,
458,
471,
481,
470,
469,
489,
459,
463,
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482,
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491,
476,
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0.47412109375
] |
[
"485",
"489",
"483",
"469",
"481",
"478"
] |
What are the components required for cardiac muscle tissue engineering?
|
query-test-82
|
[
502,
516,
504,
517,
175,
180,
849,
166,
499,
513,
160,
509,
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167,
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[
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0.40234375,
0.401123046875
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[
"518",
"530",
"502",
"514"
] |
What are the key factors to consider when engineering cardiac muscle tissue?
|
query-test-83
|
[
502,
504,
516,
175,
517,
164,
160,
513,
165,
180,
166,
179,
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849,
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[
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] |
[
"517",
"513",
"504",
"502",
"518"
] |
What does the echocardiography data reveal about the effects of the PEUU cardiac patch on heart function?
|
query-test-84
|
[
509,
512,
504,
510,
521,
516,
511,
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513,
46,
490,
44,
529,
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16,
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36,
515,
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[
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0.299560546875,
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[
"512",
"509"
] |
What insights can be drawn from the echocardiography data regarding cardiac function post-treatment?
|
query-test-85
|
[
512,
509,
526,
504,
514,
521,
513,
36,
29,
523,
531,
490,
516,
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[
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0.28076171875,
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[
"512",
"509"
] |
How does electrical stimulation contribute to the functional assembly of engineered myocardium?
|
query-test-86
|
[
513,
514,
504,
502,
515,
521,
490,
509,
516,
896,
528,
857,
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491,
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167,
660,
1013,
180,
160,
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[
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0.396484375
] |
[
"513",
"515",
"514"
] |
How do bone and articular cartilage differ in their ability to regenerate spontaneously?
|
query-test-87
|
[
503,
176,
847,
5,
53,
846,
164,
46,
768,
44,
210,
208,
27,
898,
209,
16,
865,
2,
643,
76,
500,
878,
891,
889,
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[
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0.446044921875,
0.446044921875
] |
[
"503"
] |
What are the specific conditions under which skin synthesis in vivo fails to occur?
|
query-test-88
|
[
539,
549,
533,
782,
788,
551,
783,
566,
545,
781,
601,
557,
750,
546,
368,
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556,
365,
340,
560,
565,
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564,
559,
550
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[
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0.3779296875,
0.377197265625
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[
"546",
"541",
"545"
] |
How might growth factors influence the process of skin regeneration?
|
query-test-89
|
[
559,
632,
533,
566,
689,
690,
248,
687,
630,
601,
750,
678,
387,
768,
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661,
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611,
249,
164,
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327,
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[
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0.44287109375,
0.439453125
] |
[
"558"
] |
What are the key steps involved in the synthesis of skin in vitro and in vivo?
|
query-test-90
|
[
533,
549,
750,
783,
557,
788,
782,
556,
539,
551,
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784,
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790,
755,
751,
752,
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727,
632
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[
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] |
[
"539",
"556",
"545",
"557",
"549"
] |
How do the effects of growth factors compare to pharmacological agents in skin regeneration?
|
query-test-91
|
[
558,
687,
387,
164,
533,
248,
490,
631,
849,
559,
689,
759,
180,
630,
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476,
685,
327,
566,
633,
734,
678,
750
] |
[
0.5625,
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0.4169921875,
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0.416015625,
0.416015625,
0.415771484375
] |
[
"558"
] |
What is the significance of the dermal-epidermal junction in the context of skin synthesis?
|
query-test-92
|
[
783,
784,
539,
549,
551,
781,
548,
779,
788,
533,
782,
566,
550,
557,
750,
752,
537,
773,
755,
630,
545,
619,
242,
540,
632
] |
[
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0.435302734375,
0.427001953125
] |
[
"544",
"546"
] |
In what ways might the interaction between wound contraction and skin regeneration be depicted?
|
query-test-93
|
[
559,
640,
560,
769,
988,
661,
689,
973,
768,
660,
622,
636,
750,
633,
638,
611,
659,
979,
687,
248,
632,
962,
691,
972,
619
] |
[
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] |
[
"561",
"558",
"566",
"564",
"562"
] |
What are the qualitative aspects of the 'Isomorphous and synchronized tissue replacement rule' in skin regeneration?
|
query-test-94
|
[
565,
566,
564,
533,
689,
788,
164,
690,
611,
661,
969,
559,
632,
750,
784,
956,
968,
551,
687,
159,
327,
561,
557,
768,
502
] |
[
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0.43115234375,
0.430419921875
] |
[
"565"
] |
How do the regenerative abilities of different reactants compare in terms of their effectiveness?
|
query-test-95
|
[
558,
734,
764,
777,
697,
389,
937,
533,
383,
628,
780,
387,
159,
178,
782,
531,
952,
730,
363,
775,
776,
317,
166,
781,
759
] |
[
0.4677734375,
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0.289306640625,
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0.287109375,
0.286865234375
] |
[
"558",
"541"
] |
What are the main layers of the skin and their associated structures?
|
query-test-96
|
[
537,
540,
758,
242,
542,
355,
547,
552,
618,
967,
968,
752,
548,
533,
550,
538,
570,
650,
825,
569,
827,
996,
443,
230,
574
] |
[
0.509765625,
0.50390625,
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0.445068359375,
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0.429443359375,
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0.368408203125,
0.3662109375,
0.365966796875,
0.361572265625
] |
[
"570"
] |
How does the skin's ability to cool itself through sweat evaporation work?
|
query-test-97
|
[
600,
550,
548,
570,
569,
768,
568,
242,
559,
601,
552,
769,
619,
962,
537,
557,
266,
661,
750,
241,
632,
967,
574,
783,
961
] |
[
0.552734375,
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0.386962890625,
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0.347412109375,
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0.294189453125,
0.28857421875,
0.284423828125,
0.283447265625,
0.2822265625,
0.2783203125
] |
[
"600"
] |
What are the specific molecular pathways involved in the induced regeneration of organs in adults?
|
query-test-98
|
[
690,
689,
613,
631,
566,
661,
632,
533,
521,
611,
969,
691,
340,
740,
737,
767,
641,
126,
564,
956,
327,
788,
972,
749,
973
] |
[
0.5908203125,
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0.5791015625,
0.52001953125,
0.49365234375,
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0.40380859375,
0.3984375,
0.395263671875,
0.388671875,
0.388671875,
0.387451171875
] |
[
"689"
] |
What role do myofibroblasts play in wound contraction?
|
query-test-99
|
[
661,
666,
689,
636,
979,
328,
668,
560,
559,
669,
663,
690,
973,
670,
988,
1014,
924,
930,
630,
990,
991,
686,
972,
687,
1013
] |
[
0.5185546875,
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0.50732421875,
0.501953125,
0.494384765625,
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0.42578125,
0.420654296875,
0.416259765625,
0.40673828125,
0.406005859375,
0.4052734375
] |
[
"670",
"669",
"666",
"636"
] |
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